Glossary entry

English term or phrase:

Cytoxicity was observed at 2.5 log10

Chinese translation:

在2.5对数级观察到细胞毒性

Added to glossary by Jianming Sun
Feb 5, 2004 14:23
20 yrs ago
English term

Cytoxicity was observed at 2.5 log10.

English to Chinese Medical Biology (-tech,-chem,micro-) virus
Hi the toughest question:
In the result of an inactivation test of viruses with some culture cells inoculated with viruses, the sentence is “Results from hydrogen peroxide gas plasma sterilization half cycles challenged with hiv-1 are shown in Table 1. The titer of the virus control was 6.5 log10 for the first cycle and 6.25 log10 for the second half cycle. Cytoxicity was observed at 2.5 log10. Infectivity was not detected in the test samples at any dilution in any of the four replicates tested from the two cycles (2.5 log 10 for both cycles). Taking the toxicity results into consideration, the reduction in the HIV-1 titer was ≥3.75 log10 in the first sterilization cycle and ≥4.0 log10 in the second.” Question No.1: Does "Cytoxicity was observed at 2.5log10" mean there are about 102.5 viruses causing cytoxicity? Question No. 2: what does the “(2.5 log 10 for both cycles).”? Question No.3: How did they calculated the 3.75 and 4.0 log reductions ? Thanks!

Discussion

Non-ProZ.com Feb 6, 2004:
You are right �������ѧ�ֲᣬ������ԡ�лл��
Non-ProZ.com Feb 6, 2004:
����� ����˯������У���ͻȻ����ˡ�ԭ�����Ӣ�IJ���Ϲ���ϸ�����Եķ�����һ����δ��ӡ�������������Ҫ�ǽ��������ֵ����ϸ���ϣ�ͨ���������ǰ��IJ�����ɵ�ʴ����ж����Ч�������ǿ���Ҫ�ų����黷����ϸ����ɵ��𺦣���CYTOTOCITY����������һ���������飬���в��ò����������ϸ�������������Ȼ����δ��Ⱦ����ҲҪ����ϸ������CYTOTOCITY����ã��ʡ�Cytoxicity was observed at 2.5 log10��ָ��10��2��5�η���ʴ�������黷��������ɵ�Cytoxicity�����粻����Cytoxicity�������½���Ҫ��6��5�ˡ���ƪ���µļ������Ҳ�б���лл���ǵ����
Non-ProZ.com Feb 6, 2004:
Hello! �����֣���ǶԵģ�ֻ�в��������ʽд��ˡ�
Non-ProZ.com Feb 6, 2004:
CONFUSED Still confused �� As I remember It may be Log ��A - B ��= Log (A)/Log��B��
Non-ProZ.com Feb 6, 2004:
infectivity ��cytotocity ����ʱinfectivity ��cytotocity ����������£�ǰ��ָ���������������������ԭ�����鷽����ȫ���һ�û�㶮�ô���¡�������ָ���黷�������ϸ���Ķ��ԡ�
Non-ProZ.com Feb 6, 2004:
coding:gb2312 Wrong typing: cytotocity is the correct one. Thanks!
Math confusion at least : Please not;
The titer of the virus control was 6.5 log10 for the first cycle and 6.25 log10 for the second half cycle.
Cytoxicity was observed at 2.5 log10
Taking the toxicity results into consideration, the reduction in the HIV-1 titer was ��3.75 log10 in the first sterilization cycle and ��4.0 log10 in the second.��Taking the toxicity results into consideration,the reduction in the HIV-1 titer was ��3.75 log10 in the first sterilization cycle and ��4.0 log10 in the second.��
So, according to the method of your calculation: for the first cycle it should be 6.5log 10-2.5log10=4 log10; and for the second it should be 6.25log 10-2.5log10=3.75 log10 (checked, no typing errors), not conforming to ��Taking the toxicity results into consideration, the reduction in the HIV-1 titer was ��3.75 log10 in the first sterilization cycle and ��4.0 log10 in the second.��in the article. Moreover, I almost forget about logarithm But I know here 6.5 log 10 stands for 10��6.5�η� and 2.5 log 10 stands for 10��2.5�η�. I don��t think 10��6.5�η�minus 10��2.5�η�equals 10��4�η� according to your method of calculation. ������֣���û��ʱ��֧��ϰ���������лл��лл��
�ζ�HERE can be translated as Ч��as well.
Non-ProZ.com Feb 5, 2004:
exponent In the question above "mean there are about 102.5 "viruses, "the 2.5following 10 is exponent.

Proposed translations

+2
3 hrs
Selected

所观察到的细胞毒性为2.5 log10

Cytoxicity = 细胞毒性

在科学实验中处理数据时经常取其对数后绘图(换言之,使用对数坐标),使图形比例可以大为缩小;另一方面,对数运算有许多方便之处。log代表以10为底的对数。因log 10 = 1, 故log (10的n次方) =n log 10 = n。从这点出发试答上述问题如下:

Question No.1: Does "Cytoxicity was observed at 2.5log10" mean there are about 10 2.5 viruses causing cytoxicity?
No. It means about 10的2.5次方 viruses were killed?

Question No. 2: what does the “(2.5 log 10 for both cycles)” mean?
It just emphasizes “Cytoxicity was observed at 2.5 log10 for both cycles”.

Question No.3: How did they calculate the 3.75 and 4.0 log reductions?
6.25 log10 - 2.5 log10 = 3.75 log10
6.5 log10 - 2.5 log10 = 4.0 log10

以上谨供参考,希望能以此抛砖引玉。



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Note added at 2004-02-05 20:05:49 (GMT)
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After reading the text again, I think I should make a correction to the answer for Question No.1 as follows:
\"Cytoxicity was observed at 2.5 log10\" means \"Cytoxicity was observed at the titer of 2.5 log10\", i.e., 当滴定量为2.5 log10时观察到细胞毒性。


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Note added at 2004-02-06 02:34:59 (GMT)
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log A - log B = log (A/B)
So, (10的6.5次方)除以(10的2.5次方)equals 10的4次方

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Note added at 2004-02-06 06:03:51 (GMT)
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我所用的公式log A - log B = log (A/B)是对的。6.5 log10 - 2.5 log10 = log(10的6.5次方) - log(10的2.5次方) = log [(10的6.5次方)/(10的2.5次方)] = log (10的4.0次方) = 4.0 log10 。另一方面,因 log 10 =1,故6.5 log10 - 2.5 log10 = 6.5 - 2.5 = 4.0 = 4.0 log 10。

infectivity 和cytotocity确实是两回事。Infectivity是传染性。至于其它问题,我再查一查,你也可以问一下这方面的专家或你的用户。实在没有办法时就把语法关系搞清楚按照字面翻译,应该不会错。有些很专业的论文你要想完全从专业角度搞清楚恐怕很难。当然你的精神很好。



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Note added at 2004-02-06 15:12:28 (GMT) Post-grading
--------------------------------------------------

FYI: 所谓4.0 log reduction 的概念是病毒数量下降到原来的1/10,000(即10的4次方之一)。
Peer comment(s):

agree Denyce Seow : wow, I didn't notice the three questions!! You're a maths expert too!! FYI, I hate logarithms too. You must wonder how I pass my exams??? I was a GPA4.0 student though!! Haha.
7 mins
Thanks! I can tell you are very smart, but may not be hard-working! : )
neutral technotran : Note that the word cytoxicity maybe a wrong spelling. The usual spelling is cytotoxicity.
295 days
Thank you!
agree nina yang
2132 days
Thank you!
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3 KudoZ points awarded for this answer. Comment: "Thank you! Yueyin. I had better close it and forget it. "
+1
1 hr

细胞毒性 为 2.5 log 10

Is it "cytoxicity" or "cytotoxicity"??? I tried to find if there is any difference but I didn't get any good result. If they are the same, then here's my answer:

CYTOTOXICITY: Quality of being capable of producing a specific toxic action upon cells of special organs.

Cytotoxicity = 细胞毒性
简明英汉汉英医学词典
Peer comment(s):

agree chica nueva : My first thought too...AmE?
8 hrs
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